Warfarin-Rifampin Drug Interaction in a Pediatric Patient
نویسندگان
چکیده
منابع مشابه
Interaction of rifampin and warfarin.
A 72-year-old man who had been taking rifampin daily for several months was concurrently administered warfarin daily for ten weeks. During this period, the prothrombin time (PT) rose remarkably little as the dosage of warfarin was increased. With difficulty, satisfactory anticoagulation was achieved by giving warfarin 20 mg daily. On discontinuation of rifampin therapy, the PT increased signifi...
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INTRODUCTION Warfarin therapy is associated with many drug interactions that may cause a significant alteration in its anticoagulant effect. Rifampin is a widely used antimicrobial that has major interactions with several medications including warfarin due to its strong P-glycoprotein and liver enzyme inducer activity especially on CYP2C9, CYP3A4, CYP1A2 and CYP2C19. PRESENTATION We report a ...
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we estimate that there are more than 100000 patients presently on statin treatment, and that about 10% of these patients will also be on long-term warfarin therapy. I believe your Editorial was correct in highlighting the issue of safety, and to suggest that “physicians must tell their patients the truth about rosuvastatin”. However, I would add that physicians themselves should be informed of ...
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Introduction: Carcinoma of the larynx is an extremely uncommon clinical entity in pediatric age. The diagnosis of the laryngeal carcinoma is often delayed due to the low index of suspicion. The factors contributing to delayed diagnosis include the similarity of its symptoms to common benign lesions of the larynx in childhood and difficult examination of the larynx in pediatric patients. ...
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Prosthetic joint replacement is one of the most valuable medical progresses of recent decades and it’s projected to increase by 673% in the United States alone by 2030 [1]. However, prosthetic joint infection is a serious complication of arthroplasty that is associated with significant mortality, morbidity and costs [2]. Although prosthetic joint infection occurs in a relatively small proportio...
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ژورنال
عنوان ژورنال: The Journal of Pediatric Pharmacology and Therapeutics
سال: 2017
ISSN: 1551-6776
DOI: 10.5863/1551-6776-22.5.375